Methanol → 8-Benzyl-4-hydroxy-1-phenyl-1,8-diazaspiro[4.5]decan-2-one
Reaction equation
[BH4-:26].[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH2:9][CH2:10][C:11]2([C:12](=[O:23])[CH2:13][C:14](=[O:22])[N:15]2[c:16]2[cH:17][cH:18][cH:19][cH:20][cH:21]2)[CH2:24][CH2:25]1.[CH3:29][OH:30].[CH3:31][CH2:32][O:33][C:34]([CH3:35])=[O:36].[Na+:27].[OH2:28]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH2:9][CH2:10][C:11]2([CH:12]([OH:23])[CH2:13][C:14](=[O:22])[N:15]2[c:16]2[cH:17][cH:18][cH:19][cH:20][cH:21]2)[CH2:24][CH2:25]1Participants
7
Sources & evidence
- ORD record
- ord-777a96fbbe67488293778f40a866e5ba
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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