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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1177401Generated: October 31, 2026

Sodium Hydroxide → HCID 67111612, compound

https://huagongshe.com/reaction/1177401

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium HydroxideHCID 14798—
ReactantEthyl 5-(1-phenylvinyl)thiazolo[5,4-b]pyridine-2-carboxylateHCID 67111591—
SolventTetrahydrofuranHCID 8028—
ProductHCID 67111612HCID 67111612—

Reaction Conditions

Temperature25 °C

Reaction Steps

To a solution of ethyl 5-(1-phenylvinyl)thiazolo[5,4-b]pyridine-2-carboxylate (1.04 g, 3.35 mmol) in THF (12.9 mL) was added sodium hydroxide (1.0N, aq.) (3.35 mL, 3.35 mmol), and the resulting suspension was stirred at 25° C. for 5 min. The reaction solution was subsequently concentrated in vacuo at 25° C. to provide sodium 5-(1-phenylvinyl)thiazolo[5,4-b]pyridine-2-carboxylate as a light-orange solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07842685B2
Source datasetuspto-grants-2010_11
ORD IDord-1396d8daf2324c1fa14bd866947fa770
Source noteuspto-grants-2010_11