Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | Ethyl 5-(1-phenylvinyl)thiazolo[5,4-b]pyridine-2-carboxylate | HCID 67111591 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 67111612 | HCID 67111612 | — |
Reaction Steps
To a solution of ethyl 5-(1-phenylvinyl)thiazolo[5,4-b]pyridine-2-carboxylate (1.04 g, 3.35 mmol) in THF (12.9 mL) was added sodium hydroxide (1.0N, aq.) (3.35 mL, 3.35 mmol), and the resulting suspension was stirred at 25° C. for 5 min. The reaction solution was subsequently concentrated in vacuo at 25° C. to provide sodium 5-(1-phenylvinyl)thiazolo[5,4-b]pyridine-2-carboxylate as a light-orange solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07842685B2 |
|---|
| Source dataset | uspto-grants-2010_11 |
|---|
| ORD ID | ord-1396d8daf2324c1fa14bd866947fa770 |
|---|
| Source note | uspto-grants-2010_11 |
|---|