反应详情

Reaction of 3-amino-6-(1-phenylcyclopropyl)pyridine-2(1H)-thione (50.0 mg, 206 μmol) and 4-bromo-2-fluorobenzaldehyde (44.0 mg, 217 μmol) according to Reference U and the general procedure for oxidative condensation of 3-aminopyridine-2-thione with aryl aldehydes gave 2-(4-bromo-2-fluorophenyl)-5-(1-phenylcyclopropyl)thiazolo[5,4-b]pyridine as a light yellow solid. MS (ESI) m/z: Calculated: 424.0; Observed: 424.9 (M++1).