反应详情

Reaction of 3-amino-6-(1-phenylcyclopropyl)pyridine-2(1H)-thione (27.3 mg, 113 μmol) and 2,4-difluorobenzoyl chloride (13.8 μl, 113 μmol) according to Reference V and the general procedure for the condensation of 3-aminopyridine-2-thione with aryl acid chlorides to give 2-(2,4-difluorophenyl)-5-(1-phenylcyclopropyl)thiazolo[5,4-b]pyridine as a white solid. MS (ESI) m/z: Calculated: 364.1; Observed: 365.0 (M++1).