反应详情

Reaction of 3-amino-6-(1-phenylcyclopropyl)pyridine-2(1H)-thione (52.6 mg, 0.217 mmol) and 4-fluorobenzaldehyde (22 μl, 0.206 mmol) according to Reference V and the general procedure for the condensation of 3-aminopyridine-2-thione with aryl acid chlorides gave 2-(4-fluorophenyl)-5-(1-phenylcyclopropyl)thiazolo[5,4-b]pyridine as a white solid. MS (ESI) m/z: Calculated: 346.1; Observed: 347.1 (M++1).