HuagongsheHuagongshe Chemistry Print Report · For research reference only
(2-Methoxyethyl)(methyl)amine → 3-fluoro-N-(2-methoxyethyl)-N-methyl-4-(5-(1-phenylcyclopropyl)-[1,3]thiazolo[5,4-b]pyridin-2-yl)benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (2-Methoxyethyl)(methyl)amine | HCID 300977 | — |
| Reactant | 3-Fluoro-4-(5-(1-phenylcyclopropyl)thiazolo[5,4-b]pyridin-2-yl)benzoic acid | HCID 57394406 | — |
| Product | 3-fluoro-N-(2-methoxyethyl)-N-methyl-4-(5-(1-phenylcyclopropyl)-[1,3]thiazolo[5,4-b]pyridin-2-yl)benzamide | HCID 59174844 | — |
Reaction Steps
The title compound was synthesized using the procedure described in Example 105 above, with 3-fluoro-4-(5-(1-phenylcyclopropyl)thiazolo[5,4-b]pyridin-2-yl)benzoic acid (93 mg, 0.238 mmol) and N-(2-methoxyethyl)methylamine (31 μl, 0.286 mmol). MS (ESI) m/z: Calculated: 461.2; Observed: 462.1 (M++1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07842685B2 |
| Source dataset | uspto-grants-2010_11 |
| ORD ID | ord-355c112b93a34be0bde7e82c9eeae8eb |
| Source note | uspto-grants-2010_11 |