Sodium ion → 2-(3-Fluoro-phenyl)-4-methyl-pyrimidine-5-carboxylic acid (6-trifluoromethyl-indol-1-yl)-amide

HRID 117817Notes

Reaction equation

HRID 117817 reaction equation
[C:37](=[O:38])([O-:39])[O-:40].[F:18][C:19]([c:20]1[cH:21][cH:22][c:23]2[cH:24][cH:25][n:26]([NH2:29])[c:27]2[cH:28]1)([F:30])[F:31].[F:1][c:2]1[cH:3][c:4](-[c:8]2[n:9][cH:10][c:11]([C:15](=[O:16])[OH:17])[c:12]([CH3:14])[n:13]2)[cH:5][cH:6][cH:7]1.[Na+:41].[Na+:42].[O:32]=[CH:33][N:34]([CH3:35])[CH3:36]>>[F:1][c:2]1[cH:3][c:4](-[c:8]2[n:9][cH:10][c:11]([C:15](=[O:17])[NH:29][n:26]3[cH:25][cH:24][c:23]4[cH:22][cH:21][c:20]([C:19]([F:18])([F:30])[F:31])[cH:28][c:27]43)[c:12]([CH3:14])[n:13]2)[cH:5][cH:6][cH:7]1

Participants

6

Reactant 5

HCID 923Sodium ion2×HCID 6228DimethylformamideHCID 19660Carbonate IonHCID 617025872-(3-Fluorophenyl)-4-methylpyrimidine-5-carboxylic acidHCID 685531851H-Indol-1-amine, 6-(trifluoromethyl)-

Product 1

HCID 591999662-(3-Fluoro-phenyl)-4-methyl-pyrimidine-5-carboxylic acid (6-trifluoromethyl-indol-1-yl)-amide

Sources & evidence

ORD record
ord-7fc71751558e4fff95bf4270faf86362
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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