Toluene → HCID 131726612, compound

HRID 1178170Notes

Reaction equation

HRID 1178170 reaction equation
[C:1]([Cl:6])(=[O:5])[C:2](Cl)=[O:3].COC[CH2:10][O:11][CH2:12][CH2:13][O:14][CH2:15][CH2:16][O:17][CH2:18][C:19](O)=O.[C:22]1(C)C=CC=CC=1>N1C=CC=CC=1>[CH3:10][O:11][CH2:12][CH2:13][O:14][CH2:15][CH2:16][O:17][CH2:18][CH2:19][CH2:22][O:3][CH2:2][C:1]([Cl:6])=[O:5]

Participants

5

Reactant 3

HCID 1140TolueneHCID 65578Oxalyl chlorideHCID 98593242,5,8,11-Tetraoxatridecan-13-oic acid

Product 1

HCID 131726612HCID 131726612, compoundYield 99%

Reagents, catalysts & solvents 1

HCID 1049PyridineCatalyst

Procedure

(CH3(OCH2CH2)3CH2OCH2COCl) was prepared according to Procedure 1. Oxalyl chloride (3.6 mL, 0.041 mol); {2-[2-(2-methoxy-ethoxy)-ethoxy]-ethoxy}-acetic acid (3.3 g, 0.15 mol); pyridine (0.1 mL, 1 mmol) and anhydrous toluene (10 mL) to give CH3(OCH2CH2)3CH2OCH2COCl as yellow oil (3.5 g, 99%). This compound was used without any further purification.

Workup

  1. custom(CH3(OCH2CH2)3CH2OCH2COCl) was prepared

Sources & evidence

ORD record
ord-3c560266ba7246c3813e8b3a210bf2fe
Source dataset
uspto-grants-2007_10
Patent number
US07276286B2

Reaction notes

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