Tetrahydrofuran → 2-[8-(Benzyloxy)-5-chloroquinolin-7-yl]-1-[3-(5-methyl-2-thienyl)phenyl]ethanol
Reaction equation
[Br:1][c:2]1[cH:3][c:4](-[c:8]2[s:9][c:10]([CH3:13])[cH:11][cH:12]2)[cH:5][cH:6][cH:7]1.[CH2:14]([Li:15])[CH2:16][CH2:17][CH3:18].[CH2:19]1[CH2:20][CH2:21][CH2:22][CH2:23][CH2:24]1.[CH2:25]([c:26]1[cH:27][cH:28][cH:29][cH:30][cH:31]1)[O:32][c:33]1[c:34]([CH2:44][CH:45]=[O:46])[cH:35][c:36]([Cl:43])[c:37]2[cH:38][cH:39][cH:40][n:41][c:42]12.[O:47]1[CH2:48][CH2:49][CH2:50][CH2:51]1>>[c:2]1([CH:45]([CH2:44][c:34]2[c:33]([O:32][CH2:25][c:26]3[cH:27][cH:28][cH:29][cH:30][cH:31]3)[c:42]3[c:37]([c:36]([Cl:43])[cH:35]2)[cH:38][cH:39][cH:40][n:41]3)[OH:46])[cH:3][c:4](-[c:8]2[s:9][c:10]([CH3:13])[cH:11][cH:12]2)[cH:5][cH:6][cH:7]1Participants
6
Sources & evidence
- ORD record
- ord-d5d7a69a1f7140dc8c5f8cbbc2fa0e2b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
Loading…