Hydrochloric Acid → HCID 131726616, compound

Participants

Reaction Steps

A mixture of 0.81 mmol of butyryl chloride and 0.673 mmol of AlCl3 in 2 ml of anhydrous dichloromethane is added, in small portions, to 0.135 mmol of the product of Example 3 in 2 ml of dichloromethane at 0° C. The reaction mixture is stirred for 4 hours at ambient temperature and then poured into a 10% HCl solution. After conventional treatment of the organic phases and evaporation thereof under reduced pressure, chromatography of the residue over silica gel (dichloromethane/methanol) allows the expected product to be isolated.

Provenance & Evidence