HCID 11998771, compound → HCID 86607427, compound

Participants

Reaction Steps

N-{1-(3,3,3-Trifluoro-N-methylpropanamido)-2-(S)-(3,4-dichlorophenyl)-4-[3-oxo-3,4-dihydro-2H-spiro(isoquinoline-1,4′-piperidin)-1′-yl]butan-2-yl}-N-methylbenzamide (442 mg) was dissolved in chloroform, and 4N HCl-1,4-dioxane (160 μL) was added thereto. The solvent was concentrated under reduced pressure. Ether was added to the residue, followed by filtration and drying, to thereby give the title compound (391 mg, 84.0%) as white powder.

Provenance & Evidence