Benzenamine hydrochloride (1:1) → HCID 577487, compound

HRID 1178343Notes

Reaction equation

HRID 1178343 reaction equation
Cl.[NH2:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1.[C:9](Cl)(=[O:13])[C:10]([Cl:12])=[O:11]>C1C=CC=CC=1>[O:13]=[C:9]([NH:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1)[C:10]([Cl:12])=[O:11]

Participants

4

Reactant 2

HCID 8870Benzenamine hydrochloride (1:1)HCID 65578Oxalyl chloride

Product 1

HCID 577487HCID 577487, compoundYield 76.6%

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent

Procedure

Similar to Referential Example 1, aniline hydrochloride (3.0 g) was dissolved in benzen (10 mL), and oxalyl chloride (10 mL) was added thereto under cooling with ice. The temperature of the mixture was then returned to room temperature, and the mixture was stirred overnight. The reaction mixture was concentrated under reduced pressure, to thereby give the title compound (3.26 g, 76.6%) as a brown oil.

Workup

  1. temperatureunder cooling with ice
  2. customwas then returned to room temperature
  3. concentrationThe reaction mixture was concentrated under reduced pressure

Sources & evidence

ORD record
ord-61e5e6a3995f4fe996b9b0b25aa13996
Source dataset
uspto-grants-2007_10
Patent number
US07276511B2

Reaction notes

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