反应详情

tert-Butyl (2-oxo-1,2,3,4-tetrahydro-1,5-naphthyridine-3-yl)carbamate (Method 26, 263 mg, 1 mmol) was dissolved in DCM (10 mL) and treated with 4M HCl in dioxan (10 mL). After stirring at ambient temperature for 30 mins. the reaction mixture was evaporated under reduced pressure and the residue triturated with ether (20 mL), to give a white solid which was collected by filtration, washed with ether and dried. (234 mg, 100%).

1. customthe reaction mixture was evaporated under reduced pressure
2. customthe residue triturated with ether (20 mL)
3. customto give a white solid which
4. filtrationwas collected by filtration
5. washwashed with ether
6. customdried