Indole → HCID 23118673, compound

HRID 1178715Notes

Reaction equation

[CH:1]1[C:14]2[C:5](=[N:6][CH:7]=[C:8]3[C:13]=2[CH:12]=[CH:11][CH:10]=[CH:9]3)[CH:4]=[CH:3][CH:2]=1.[CH3:15][N:16]([CH3:26])[C:17]1[CH:25]=[CH:24][C:20]([C:21](Cl)=[O:22])=[CH:19][CH:18]=1.[NH:27]1[C:35]2[C:30](=[CH:31][CH:32]=[CH:33][CH:34]=2)[CH:29]=[CH:28]1>>[CH3:15][N:16]([CH3:26])[C:17]1[CH:25]=[CH:24][C:20]([C:21]([N:6]2[CH:7]([C:29]3[C:30]4[C:35](=[CH:34][CH:33]=[CH:32][CH:31]=4)[NH:27][CH:28]=3)[C:8]3[C:13](=[CH:12][CH:11]=[CH:10][CH:9]=3)[C:14]3[CH:1]=[CH:2][CH:3]=[CH:4][C:5]2=3)=[O:22])=[CH:19][CH:18]=1

Participants

Reactant 3

HCID 798Indole

HCID 9189Phenanthridine

HCID 44007824-(Dimethylamino)benzoyl chloride

Product 1

HCID 23118673HCID 23118673, compound

Procedure

(4-Dimethylamino-phenyl)-[6-(1H-indol-3-yl)-6H-phenanthridin-5-yl]-methanone was prepared from phenanthridine, 4-dimethylaminobenzoyl chloride, and indole according to GP 2. Yield, 55%. (+)-ESI-MS: m/z=444 [M+H]+, 327. [M-indole+H]+, 148.

Workup

customYield

Sources & evidence

ORD record: ord-093931ff379c4c419811f330f60ec175
Source dataset: uspto-grants-2007_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07276606B2

Reaction notes

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