Indole → HCID 23118669, compound

HRID 1178739Notes

Reaction equation

HRID 1178739 reaction equation
[CH:1]1[C:14]2[C:5](=[N:6][CH:7]=[C:8]3[C:13]=2[CH:12]=[CH:11][CH:10]=[CH:9]3)[CH:4]=[CH:3][CH:2]=1.[CH:15]1([C:21](Cl)=[O:22])[CH2:20][CH2:19][CH2:18][CH2:17][CH2:16]1.[NH:24]1[C:32]2[C:27](=[CH:28][CH:29]=[CH:30][CH:31]=2)[CH:26]=[CH:25]1>>[CH:15]1([C:21]([N:6]2[CH:7]([C:26]3[C:27]4[C:32](=[CH:31][CH:30]=[CH:29][CH:28]=4)[NH:24][CH:25]=3)[C:8]3[C:13](=[CH:12][CH:11]=[CH:10][CH:9]=3)[C:14]3[CH:1]=[CH:2][CH:3]=[CH:4][C:5]2=3)=[O:22])[CH2:20][CH2:19][CH2:18][CH2:17][CH2:16]1

Participants

4

Reactant 3

HCID 798IndoleHCID 9189PhenanthridineHCID 75938Cyclohexanecarbonyl chloride

Product 1

HCID 23118669HCID 23118669, compound

Procedure

Cyclohexyl-[6-(1H-indol-3-yl)-6H-phenanthridin-5-yl]-methanone was prepared from phenanthridine, cyclohexanecarboxylic acid chloride, and indole according to GP 2. Yield, 7%. (+)-ESI-MS: m/z=407 [M+H]+, 290 [M-indole+H]+, 180.

Workup

  1. customYield

Sources & evidence

ORD record
ord-383c6ec19c534403aba9add172541dc7
Source dataset
uspto-grants-2007_10
Patent number
US07276606B2

Reaction notes

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