反应详情

As described for example 66, 129 mg of the polar diastereomer of N′-[2-(1H-indol-3-yl)-ethyl]-N,N,N′-trimethyl-1-phenyl-cyclohexane-1,4-diamine were also obtained and were converted into the corresponding dihydrochloride while warm in 2-butanone/acetone (15 ml/3 ml) with chlorotrimethylsilane (121 μl) (white solid; 141 mg; m.p. 198-206° C.).

1. customwere also obtained