N,N-Dimethylethylenediamine → HCID 67210695, compound

HRID 1179120Notes

Reaction equation

HRID 1179120 reaction equation
[CH3:1][N:2]([CH3:6])[CH2:3][CH2:4][NH2:5].[CH:7]1([C:13]2[S:14][C:15]3[C:21](=[O:22])[CH:20]=[C:19](NCCN(C)C)[C:18](=[O:29])[C:16]=3[N:17]=2)[CH2:12][CH2:11][CH2:10][CH2:9][CH2:8]1>>[CH:7]1([C:13]2[S:14][C:15]3[C:21](=[O:22])[C:20]([NH:5][CH2:4][CH2:3][N:2]([CH3:6])[CH3:1])=[CH:19][C:18](=[O:29])[C:16]=3[N:17]=2)[CH2:8][CH2:9][CH2:10][CH2:11][CH2:12]1

Participants

3

Reactant 2

HCID 66053N,N-DimethylethylenediamineHCID 67210759HCID 67210759, compound

Product 1

HCID 67210695HCID 67210695, compound

Procedure

The experimental protocol used is identical to that described for Stage 15.4 of Example 15, intermediate 101.4 replacing intermediate 15.3 and N,N-dimethylethylene diamine replacing aniline. A mixture of 80% and 9% of 2-cyclohexyl-5-{[2-(dimethylamino)ethyl]amino}-1,3-benzothiazole-4,7-dione and of 2-cyclohexyl-6-{[2-(dimethylamino)ethyl]amino}-1,3-benzothiazole-4,7-dione is obtained.

Sources & evidence

ORD record
ord-f5a9b11195cd40baa2ceaee26362ea6d
Source dataset
uspto-grants-2007_10
Patent number
US07279467B2

Reaction notes

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