HRID1179341

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CC(C)(C)OC(=O)CC1CCN(CC(=O)O)C(=O)c2ccccc21

HCID69434194

未命名化合物

结构：NC[C@H]1CC[C@H](Nc2nc3ccccc3[nH]2)CC1

HCID178511276

未命名化合物

PRODUCTS

生成物

结构：CC(C)(C)OC(=O)CC1CCN(CC(=O)NCC2CCC(Nc3nc4ccccc4[nH]3)CC2)C(=O)c2ccccc21

HCID86760556

未命名化合物

PROCEDURE

实验过程

Analogously to Example V, compound 3 was reacted with 0.57 g (1.8 mmol) of compound 7 and the mixture was purified; 0.5 g of white amorphous powder; ESI-MS [M+H+]: 560.

WORKUP

后处理

customthe mixture was purified

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-e9976777f4164ec98c84a2d90cf5d03b
来源数据集: uspto-grants-2007_10
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07279468B2
来源说明: uspto-grants-2007_10

反应 SMILES

[C:1]([O:5][C:6](=[O:24])[CH2:7][CH:8]1[C:14]2[CH:15]=[CH:16][CH:17]=[CH:18][C:13]=2[C:12](=[O:19])[N:11]([CH2:20][C:21]([OH:23])=O)[CH2:10][CH2:9]1)([CH3:4])([CH3:3])[CH3:2].[NH2:25][CH2:26][C@H:27]1[CH2:32][CH2:31][C@H:30]([NH:33][C:34]2[NH:38][C:37]3[CH:39]=[CH:40][CH:41]=[CH:42][C:36]=3[N:35]=2)[CH2:29][CH2:28]1>>[NH:35]1[C:36]2[CH:42]=[CH:41][CH:40]=[CH:39][C:37]=2[N:38]=[C:34]1[NH:33][CH:30]1[CH2:29][CH2:28][CH:27]([CH2:26][NH:25][C:21](=[O:23])[CH2:20][N:11]2[CH2:10][CH2:9][CH:8]([CH2:7][C:6]([O:5][C:1]([CH3:3])([CH3:4])[CH3:2])=[O:24])[C:14]3[CH:15]=[CH:16][CH:17]=[CH:18][C:13]=3[C:12]2=[O:19])[CH2:32][CH2:31]1