Pyrrolidine → 1-(2-Methyl-4-pyrrolidin-1-ylmethyl-phenyl)-4-pyrrolidin-1-ylmethyl-pyrrolidine

HRID 1179398Notes

Reaction equation

HRID 1179398 reaction equation
[CH3:1][C:2]1[CH:3]=[C:4]([CH:7]=[CH:8][C:9]=1[N:10]1[CH2:15][CH2:14][CH:13]([CH2:16][N:17]2[CH2:21][CH2:20][CH2:19][CH2:18]2)[CH2:12]C1)[CH:5]=O.[NH:22]1[CH2:26][CH2:25][CH2:24][CH2:23]1>>[CH3:1][C:2]1[CH:3]=[C:4]([CH2:5][N:22]2[CH2:26][CH2:25][CH2:24][CH2:23]2)[CH:7]=[CH:8][C:9]=1[N:10]1[CH2:12][CH:13]([CH2:16][N:17]2[CH2:18][CH2:19][CH2:20][CH2:21]2)[CH2:14][CH2:15]1

Participants

3

Reactant 2

HCID 31268PyrrolidineHCID 589780393-Methyl-4-(4-pyrrolidin-1-ylmethyl-piperidin-1-yl)-benzaldehyde

Product 1

HCID 102459061-(2-Methyl-4-pyrrolidin-1-ylmethyl-phenyl)-4-pyrrolidin-1-ylmethyl-pyrrolidine

Procedure

Prepared from the product of Example 66 and pyrrolidine.

Sources & evidence

ORD record
ord-fb6ff8dc1c814ec3b75f42638df35b40
Source dataset
uspto-grants-2007_10
Patent number
US07279491B2

Reaction notes

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