Piperidine → 1-[3-Methyl-4-(4-pyrrolidin-1-ylmethyl-piperidin-1-yl)-benzyl]-pyrrolidine

HRID 1179399Notes

Reaction equation

HRID 1179399 reaction equation
[CH3:1][C:2]1[CH:3]=[C:4]([CH:7]=[CH:8][C:9]=1[N:10]1[CH2:15][CH2:14][CH:13]([CH2:16][N:17]2[CH2:21][CH2:20][CH2:19][CH2:18]2)[CH2:12][CH2:11]1)[CH:5]=O.[NH:22]1[CH2:27][CH2:26][CH2:25][CH2:24]C1>>[CH3:1][C:2]1[CH:3]=[C:4]([CH:7]=[CH:8][C:9]=1[N:10]1[CH2:15][CH2:14][CH:13]([CH2:16][N:17]2[CH2:21][CH2:20][CH2:19][CH2:18]2)[CH2:12][CH2:11]1)[CH2:5][N:22]1[CH2:24][CH2:25][CH2:26][CH2:27]1

Participants

3

Reactant 2

HCID 8082PiperidineHCID 589780393-Methyl-4-(4-pyrrolidin-1-ylmethyl-piperidin-1-yl)-benzaldehyde

Product 1

HCID 103152901-[3-Methyl-4-(4-pyrrolidin-1-ylmethyl-piperidin-1-yl)-benzyl]-pyrrolidine

Procedure

Prepared from the product of Example 66 and piperidine.

Sources & evidence

ORD record
ord-95aecdde9c784c7fa402f751bdb29f0e
Source dataset
uspto-grants-2007_10
Patent number
US07279491B2

Reaction notes

Loading…