Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1179643Generated: October 29, 2026

Hexahydro-2-benzimidazolinone → 1-(3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)octahydro-2H-benzimidazol-2-one

https://huagongshe.com/reaction/1179643

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHexahydro-2-benzimidazolinoneHCID 101982—
Reactant5-{4-[2-(3-Iodophenyl)ethyl]-1-piperazinyl)2-methylquinolineHCID 57444355—
Product1-(3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)octahydro-2H-benzimidazol-2-oneHCID 57478384100%

Reaction Steps

The title compound was prepared in 100% yield according to the general procedure for the preparation of the amides, ureas and carbamates (Method A) starting from 5-{4-[2-(3-iodophenyl)ethyl]-1-piperazinyl}2-methylquinoline and octahydro-2H-benzimidazol-2-one.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07279481B2
Source datasetuspto-grants-2007_10
ORD IDord-1ee0b002ac864c76a8203ecb8bc5578a
Source noteuspto-grants-2007_10