HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → HCID 22047722, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | HCID 22047823 | HCID 22047823 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 22047722 | HCID 22047722 | — |
Reaction Steps
The crude 4-(6-methoxy-pyridin-3-ylcarbamoyl)-butyryl chloride was redissolved in dichloromethane (25 mL). Thionyl chloride (5.95 g, 50 mmol) was added and the solution was heated to reflux overnight. The solvent and excess thionyl chloride were evaporated in vacuo, yielding 6′-methoxy-4,5-dihydro-3H-[1,3′]bipyridinyl-2,6-dione hydrochloride, which was used without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07279470B2 |
| Source dataset | uspto-grants-2007_10 |
| ORD ID | ord-7adb2829e8b246f1808a7d9d416f69eb |
| Source note | uspto-grants-2007_10 |