Carbamic chloride, N-methyl-N-phenyl- → HCID 10308410, compound

HRID 1179710Notes

Reaction equation

HRID 1179710 reaction equation
[C:1]([O:5][C:6]1[CH:11]=[CH:10][C:9]([OH:12])=[CH:8][CH:7]=1)([CH3:4])([CH3:3])[CH3:2].[CH3:13][N:14]([C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1)[C:15](Cl)=[O:16]>ClCCl>[C:1]([O:5][C:6]1[CH:7]=[CH:8][C:9]([O:12][C:15](=[O:16])[N:14]([CH3:13])[C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)=[CH:10][CH:11]=1)([CH3:4])([CH3:2])[CH3:3]

Participants

4

Reactant 2

HCID 77969Carbamic chloride, N-methyl-N-phenyl-HCID 2773621p-Tert-butoxyphenol

Product 1

HCID 10308410HCID 10308410, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

The title compound was prepared from 4-tert-butoxy-phenol and N-methyl-N-phenylcarbamoyl chloride. The crude product was subjected to flash chromatography (Quad12/25, flash 12, dichloromethane) followed by a recrystallization from ethanol (41%, crystals). HPLC-MS m/z=300.3 (M+1), Rt: 4.7 min.

Workup

  1. customfollowed by a recrystallization from ethanol (41%, crystals)

Sources & evidence

ORD record
ord-95573624b0204f8db0d77f20a4154d87
Source dataset
uspto-grants-2007_10
Patent number
US07279470B2

Reaction notes

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