HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(4-Hydroxyphenoxy)-5-(trifluoromethyl)pyridine-2-carbonitrile → (4-Chloro-phenyl)-methyl-carbamic Acid 4-(2-cyano-5-trifluoromethyl-pyridin-3-yloxy)-phenyl Ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(4-Hydroxyphenoxy)-5-(trifluoromethyl)pyridine-2-carbonitrile | HCID 4313863 | — |
| Reactant | 3-[(4-chlorophenyl)-methyl-carbamoyl]-1-methyl-3H-imidazol-1-ium iodide | HCID 22047798 | — |
| Product | (4-Chloro-phenyl)-methyl-carbamic Acid 4-(2-cyano-5-trifluoromethyl-pyridin-3-yloxy)-phenyl Ester | HCID 10151515 | — |
Reaction Steps
The title compound was prepared from 4-(2-cyano-5-trifluoromethyl-pyridin-3-yloxy)-phenol and 3-[(4-chlorophenyl)-methyl-carbamoyl]-1-methyl-3H-imidazol-1-ium iodide. The crude product was purified by preparative HPLC (25%). HPLC-MS m/z=448.2 (M+1), Rt: 5.1 min.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07279470B2 |
| Source dataset | uspto-grants-2007_10 |
| ORD ID | ord-4281690ec91541e0b9f6d56d55a09ce7 |
| Source note | uspto-grants-2007_10 |