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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1179751Generated: October 29, 2026

4-(5-Trifluoromethyl-pyridin-2-yloxy)-phenol → HCID 23635401, compound

https://huagongshe.com/reaction/1179751

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(5-Trifluoromethyl-pyridin-2-yloxy)-phenolHCID 155241—
ReactantHCID 43145426HCID 43145426—
SolventEthylacetate heptaneHCID 21899848—
ProductHCID 23635401HCID 23635401—

Reaction Steps

The title compound was prepared from 4-(5-trifluoromethyl-pyridin-2-yloxy)-phenol and 3-(cyclohexyl-methyl-carbamoyl)-1-methyl-3H-imidazol-1-ium iodide. The crude product was subjected to flash chromatography (ethyl acetate/heptane, 1:5) (80%, white crystals). HPLC-MS m/z=395.2 (M+1), Rt: 5.7 min.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07279470B2
Source datasetuspto-grants-2007_10
ORD IDord-6863598f58b941b2a44694687b49fd91
Source noteuspto-grants-2007_10