4-Hydroxy-2-methylacetophenone → HCID 69519179, compound

HRID 1179800Notes

Reaction equation

HRID 1179800 reaction equation
[OH:1][C:2]1[CH:7]=[CH:6][C:5]([C:8](=[O:10])[CH3:9])=[C:4]([CH3:11])[CH:3]=1.[CH3:12][N:13]([C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1)[C:14](Cl)=[O:15]>>[C:8]([C:5]1[CH:6]=[CH:7][C:2]([O:1][C:14](=[O:15])[N:13]([CH3:12])[C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)=[CH:3][C:4]=1[CH3:11])(=[O:10])[CH3:9]

Participants

3

Reactant 2

HCID 701334-Hydroxy-2-methylacetophenoneHCID 77969Carbamic chloride, N-methyl-N-phenyl-

Product 1

HCID 69519179HCID 69519179, compound

Procedure

The title product was prepared from 4′-hydroxy-2′-methylacetophenone and N-methyl-N-phenylcarbamoyl chloride. The crude product was subjected to preparative HPLC. (76%, white crystals). HPLC-MS: m/z=284.2 (M+1); Rt: 3.95 min.

Sources & evidence

ORD record
ord-d73068c2275a491ca393335511f4e8a6
Source dataset
uspto-grants-2007_10
Patent number
US07279470B2

Reaction notes

Loading…