Carbamic chloride, N-methyl-N-phenyl- → Methyl-phenyl-carbamic Acid benzo[d]isoxazol-3-yl Ester

HRID 1179804Notes

Reaction equation

HRID 1179804 reaction equation
[O:1]1[C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[C:3]([OH:10])=[N:2]1.[CH3:11][N:12]([C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1)[C:13](Cl)=[O:14]>>[O:1]1[C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[C:3]([O:10][C:13](=[O:14])[N:12]([CH3:11])[C:16]2[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=2)=[N:2]1

Participants

3

Reactant 2

HCID 77969Carbamic chloride, N-methyl-N-phenyl-HCID 178518983HCID 178518983, compound

Product 1

HCID 69519226Methyl-phenyl-carbamic Acid benzo[d]isoxazol-3-yl Ester

Procedure

The title product was prepared from benzo[d]isoxazol-3-ol and N-methyl-N-phenylcarbamoyl chloride. The crude product was subjected to preparative HPLC. (53%, colorless oil). HPLC-MS: m/z=291.1 (M+23); Rt: 4.05 min.

Sources & evidence

ORD record
ord-afb228d82c1f4b3581cc5480ab2888d9
Source dataset
uspto-grants-2007_10
Patent number
US07279470B2

Reaction notes

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