Phosphorus oxychloride → N-[4-(Cyano-dimethyl-methyl)-2-fluoro-benzyl]-2-(4-fluoro-phenoxy)-nicotinamide
Reaction equation
[C:1]([NH2:2])(=[O:3])[C:4]([CH3:5])([CH3:6])[c:7]1[cH:8][c:9]([F:31])[c:10]([CH2:11][NH:12][C:13]([c:14]2[c:15]([O:20][c:21]3[cH:22][cH:23][c:24]([F:27])[cH:25][cH:26]3)[n:16][cH:17][cH:18][cH:19]2)=[O:28])[cH:29][cH:30]1.[P:32]([Cl:33])([Cl:34])([Cl:35])=[O:36]>>[C:1](#[N:2])[C:4]([CH3:5])([CH3:6])[c:7]1[cH:8][c:9]([F:31])[c:10]([CH2:11][NH:12][C:13]([c:14]2[c:15]([O:20][c:21]3[cH:22][cH:23][c:24]([F:27])[cH:25][cH:26]3)[n:16][cH:17][cH:18][cH:19]2)=[O:28])[cH:29][cH:30]1Participants
3
Sources & evidence
- ORD record
- ord-a5fa408719fd4055a976b62c3b900bac
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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