HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Methylpiperazine → HCID 69517728, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Methylpiperazine | HCID 53167 | — |
| Reactant | 4-Chlorophenyl chloroformate | HCID 139059 | — |
| Reactant | Potassium Bromide | HCID 253877 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 69517728 | HCID 69517728 | — |
Reaction Steps
The hydrochloride of the title compound was prepared from 4-chlorophenyl chloroformate and 1-methylpiperazine, yield 81%. White crystals, m.p. 237-240° C.; 1H NMR (DMSO-d6): δ11.67 (br s, 1H), 7.50, 7.45, 7.24, 7.20 (AB-system, d=7.47 and 7.22; J=8.84 Hz, 4H), 4.40-3.91 (br, 2H, 3.77-2.92 (br m, 6H+water), 2.77 (s, 3H); IR (KBr): ν 1717 (C═O) cm −1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07279470B2 |
| Source dataset | uspto-grants-2007_10 |
| ORD ID | ord-07b2414d8e6841488f5e4ddf83d49a21 |
| Source note | uspto-grants-2007_10 |