Carbamic chloride, N-methyl-N-phenyl- → Methyl-phenyl-carbamic Acid 4-acetyl-pyrazol-1-yl Ester

HRID 1179909Notes

Reaction equation

HRID 1179909 reaction equation
[OH:1][N:2]1[CH:6]=[C:5]([C:7](=[O:9])[CH3:8])[CH:4]=[N:3]1.[CH3:10][N:11]([C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1)[C:12](Cl)=[O:13]>>[C:7]([C:5]1[CH:4]=[N:3][N:2]([O:1][C:12](=[O:13])[N:11]([CH3:10])[C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)[CH:6]=1)(=[O:9])[CH3:8]

Participants

3

Reactant 2

HCID 77969Carbamic chloride, N-methyl-N-phenyl-HCID 220479131-(1-Hydroxy-1H-pyrazol-4-yl)ethanone

Product 1

HCID 69518094Methyl-phenyl-carbamic Acid 4-acetyl-pyrazol-1-yl Ester

Procedure

The title compound was prepared from 1-hydroxy-4-acetylpyrazole and N-methyl-N-phenylcarbamoyl chloride applying the general procedure 8. The crude product was purified by flash chromatography (Quad flash 12, EtOAc-heptane) (89%, oil).

Workup

  1. customThe crude product was purified by flash chromatography (Quad flash 12, EtOAc-heptane) (89%, oil)

Sources & evidence

ORD record
ord-d622623ef6714d079d2be0b50f9252f2
Source dataset
uspto-grants-2007_10
Patent number
US07279470B2

Reaction notes

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