HRID1179967

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID2736204

1-(2,4-dimethoxyphenyl)piperazine

C12H18N2O2

结构：O=C(Cl)Oc1ccc(Oc2ccc(C(F)(F)F)cn2)cc1

HCID22047762

未命名化合物

PRODUCTS

生成物

结构：COc1ccc(N2CCN(C(=O)Oc3ccc(Oc4ccc(C(F)(F)F)cn4)cc3)CC2)c(OC)c1

HCID69517925

未命名化合物

收率 69%

PROCEDURE

实验过程

The title compound was prepared from 4-(5-trifluoromethyl-pyridin-2-yloxy)-phenyl chloroformate and 1-(2,4-dimethoxyphenyl)-piperazine. Purified by flash chromatography (ethyl acetate—heptane 1:4), yield 69%. White crystals, m.p. 98-99° C.; HPLC-MS: m/z=504 (M+1) at Rt=4.0 min.; IR (KBr): ν 1733, 1712 (C═O) cm−1.

WORKUP

后处理

customPurified by flash chromatography (ethyl acetate—heptane 1:4), yield 69%