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HRID 1179971作成日：2026年10月25日

4-(4,4-Dimethyl-2,6-dioxo-piperidin-1-yl)-phenyl chloroformate → 4-Pyridin-3-ylmethyl-piperazine-1-carboxylic acid 4-(4,4-dimethyl-2,6-dioxo-piperidin-1-yl)-phenyl Ester

https://huagongshe.com/reaction/1179971

反応式

関与物質

役割名称HCID仕込み量
反応物4-(4,4-Dimethyl-2,6-dioxo-piperidin-1-yl)-phenyl chloroformateHCID 22047895—
反応物Piperazine, 1-(3-pyridinylmethyl)-, hydrochloride (1:1)HCID 45074811—
生成物4-Pyridin-3-ylmethyl-piperazine-1-carboxylic acid 4-(4,4-dimethyl-2,6-dioxo-piperidin-1-yl)-phenyl EsterHCID 57455786—

反応手順

The title compound was prepared from 4-(4,4-dimethyl-2,6-dioxo-piperidin-1-yl)-phenyl chloroformate and 1-pyridin-3-ylmethyl-piperazine, hydrochloride, preparative HPLC (Method C) (75%, colourless oil). HPLC-MS m/z=437.2 (M+1), Rt: 1.70 min.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US07279470B2
出典データセットuspto-grants-2007_10
ORD IDord-3bd63e1d99be4d7794c21a987e14aed5
出典メモuspto-grants-2007_10