HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(2-Cyclohexyl-acetylamino)-phenyl chloroformate → 4-Pyridin-3-ylmethyl-piperazine-1-carboxylic Acid 4-(2-cyclohexyl-acetylamino)-phenyl Ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(2-Cyclohexyl-acetylamino)-phenyl chloroformate | HCID 22047886 | — |
| Reactant | Piperazine, 1-(3-pyridinylmethyl)-, hydrochloride (1:1) | HCID 45074811 | — |
| Product | 4-Pyridin-3-ylmethyl-piperazine-1-carboxylic Acid 4-(2-cyclohexyl-acetylamino)-phenyl Ester | HCID 57473680 | — |
Reaction Steps
The title compound was prepared from 4-(2-cyclohexyl-acetylamino)-phenyl chloroformate and 1-pyridin-3-ylmethyl-piperazine, hydrochloride, preparative HPLC (method C) (64%, white crystals). HPLC-MS m/z=437.4 (M+1), Rt: 2.38 min.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07279470B2 |
| Source dataset | uspto-grants-2007_10 |
| ORD ID | ord-59fb23b5947c499e819ed5c8a4d2b764 |
| Source note | uspto-grants-2007_10 |