Benzenamine, 2-chloro-N-methyl- → HCID 23635632, compound

HRID 1179997Notes

Reaction equation

HRID 1179997 reaction equation
[Cl:1][C:2]1[CH:9]=[CH:8][CH:7]=[CH:6][C:3]=1[NH:4][CH3:5].Cl[C:11]([O:13][C:14]1[CH:19]=[CH:18][C:17]([O:20][C:21]2[CH:26]=[CH:25][C:24]([C:27]([F:30])([F:29])[F:28])=[CH:23][N:22]=2)=[CH:16][CH:15]=1)=[O:12]>>[F:28][C:27]([F:30])([F:29])[C:24]1[CH:25]=[CH:26][C:21]([O:20][C:17]2[CH:18]=[CH:19][C:14]([O:13][C:11](=[O:12])[N:4]([C:3]3[CH:6]=[CH:7][CH:8]=[CH:9][C:2]=3[Cl:1])[CH3:5])=[CH:15][CH:16]=2)=[N:22][CH:23]=1

Participants

3

Reactant 2

HCID 136736Benzenamine, 2-chloro-N-methyl-HCID 220477624-(5-Trifluoromethylpyridin-2-yloxy)-phenyl chloroformate

Product 1

HCID 23635632HCID 23635632, compound

Procedure

The title product was prepared from 2-chlor-N-methylaniline and 4-(5-trifluoromethyl-pyridin-2-yloxy)-phenyl chloroformate, preparative HPLC (method C) (48%, light yellow oil). HPLC-MS m/z=423.1 (M+1), Rt: 4.98 min.

Sources & evidence

ORD record
ord-343630d4fd464f95a7b8e8a5295f3055
Source dataset
uspto-grants-2007_10
Patent number
US07279470B2

Reaction notes

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