2,2-Dimethylsuccinic anhydride → HCID 22047738, compound

HRID 1180014Notes

Reaction equation

HRID 1180014 reaction equation
[NH2:1][C:2]1[CH:3]=[CH:4][C:5]([O:8][C:9](=[O:18])[N:10]([CH3:17])[C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)=[N:6][CH:7]=1.[CH3:19][C:20]1([CH3:27])[CH2:25][C:24](=[O:26])[O:23][C:21]1=[O:22]>ClCCl>[CH3:19][C:20]([CH3:27])([CH2:25][C:24]([NH:1][C:2]1[CH:7]=[N:6][C:5]([O:8][C:9](=[O:18])[N:10]([CH3:17])[C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)=[CH:4][CH:3]=1)=[O:26])[C:21]([OH:23])=[O:22]

Participants

4

Reactant 2

HCID 870672,2-Dimethylsuccinic anhydrideHCID 69465626HCID 69465626, compound

Product 1

HCID 22047738HCID 22047738, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

A solution of methyl-phenyl-carbamic acid 5-amino-pyridin-2-yl ester (0.49 g, 2.00 mmol) and 2,2-dimethylsuccinic anhydride (0.26 g, 2.00 mmol) in dichloromethane (10 mL) was stirred at room temperature overnight. Evaporation of the solvent in vacuo yielded the title compound.

Workup

  1. customEvaporation of the solvent in vacuo

Sources & evidence

ORD record
ord-85d85f88b9204af6b51e56998d5ec9bb
Source dataset
uspto-grants-2007_10
Patent number
US07279470B2

Reaction notes

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