HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Hydroxypyridine → Methyl-phenyl-carbamic Acid 4-(pyridin-3-yloxymethyl)-phenyl Ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Hydroxypyridine | HCID 7971 | — |
| Reactant | Methyl-phenyl-carbamic Acid 4-hydroxymethyl-phenyl Ester | HCID 69518671 | — |
| Product | Methyl-phenyl-carbamic Acid 4-(pyridin-3-yloxymethyl)-phenyl Ester | HCID 69519278 | 43% |
Reaction Steps
The title compound was prepared in 43% yield as an oil using methyl-phenyl-carbamic acid 4-hydroxymethyl-phenyl ester and 3-hydroxypyridine. 1H NMR (400 MHz; CDCl3): δ 3.44 (br s, 3H), 5.12 (s, 2H), 7.17 (br s, 2H), 7.27-7.46 (m, 9H), 8.29 (br s, 1H), 8.49 (br s, 1H); HPLC-MS: m/z=335.0 (M+1); Rt=2.74 min.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07279470B2 |
| Source dataset | uspto-grants-2007_10 |
| ORD ID | ord-b3e6028fbf384d4392affc50e7b320dd |
| Source note | uspto-grants-2007_10 |