HuagongsheHuagongshe Chemistry Print Report · For research reference only
[2-(1H-Pyrazol-1-yl)phenyl]boronic acid → HCID 10477788, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | [2-(1H-Pyrazol-1-yl)phenyl]boronic acid | HCID 3296948 | — |
| Reactant | 2-[3-(3-Chloro-4-fluorophenyl)-8-fluoroimidazo[1,2-alpha]pyridin-7-yl]propan-2-ol | HCID 67486680 | — |
| Product | HCID 10477788 | HCID 10477788 | 4% |
Reaction Steps
2-[3-(3-Chloro-4-fluorophenyl)-8-fluoroimidazo[1,2-α]pyridin-7-yl]-propan-2-ol and 2-(pyrazol-1-yl)benzeneboronic acid were coupled in the same way as in Example 30 to give 2-{8-fluoro-3-[2-fluoro-2′-(pyrazol-1-yl)biphenyl-5-yl]imidazo[1,2-α]pyridin-7-yl}propan-2-ol as an off-white solid (5 mg, 4%): m/z (ES+) 431 [MH+].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07279580B2 |
| Source dataset | uspto-grants-2007_10 |
| ORD ID | ord-1bea4adcb0a54848801c0f03a49db09c |
| Source note | uspto-grants-2007_10 |