HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(5-Chloro-2-fluorophenyl)-5,5-dimethyl-1,3,2-dioxaborinane → HCID 9979330, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(5-Chloro-2-fluorophenyl)-5,5-dimethyl-1,3,2-dioxaborinane | HCID 17964834 | — |
| Reactant | 2-[3-(3-Chloro-4-fluorophenyl)-8-fluoroimidazo[1,2-alpha]pyridin-7-yl]propan-2-ol | HCID 67486680 | — |
| Product | HCID 9979330 | HCID 9979330 | 3% |
Reaction Steps
2-[3-(3-Chloro-4-fluorophenyl)-8-fluoroimidazo[1,2-α]pyridin-7-yl]-propan-2-ol and 2-(5-chloro-2-fluorophenyl)-5,5-dimethyl-[1,3,2]dioxaborinane were coupled in the same way as in Example 30 to give 2-[3-(5′-chloro-2,2′-difluorobiphenyl-5-yl)-8-fluoroimidazo[1,2-α]pyridin-7-yl]propan-2-ol as an off-white solid (6 mg, 3%): m/z (ES+) 417 [MH+].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07279580B2 |
| Source dataset | uspto-grants-2007_10 |
| ORD ID | ord-b6012c8501eb45fe9ad78c0a0fbbdd8c |
| Source note | uspto-grants-2007_10 |