HCID 17964831, compound → HCID 10250810, compound

Participants

Reaction Steps

2-[3-(3-Chloro-4-fluorophenyl)-8-fluoroimidazo[1,2-α]pyridin-7-yl]-propan-2-ol and 5-(5,5-dimethyl-[1,3,2]dioxaborinan-2-yl)-2-fluorobenzonitrile were coupled in the same way as in Example 30 to give 4,2′-difluoro-5′-[8-fluoro-7-(1-hydroxy-1-methylethyl)imidazo[1,2-α]pyridin-3-yl]biphenyl-3-carbonitrile as an off-white solid (9 mg, 5%): m/z (ES+) 408 [MH+].

Provenance & Evidence