Hydroxyamine hydrochloride → HCID 136338601, compound

HRID 1180347Notes

Reaction equation

HRID 1180347 reaction equation
[OH:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[CH:13]=[CH:12][C:11]([CH:14]=O)=[CH:10][C:9]=2[CH3:16])=[CH:4][CH:3]=1.Cl.[NH2:18][OH:19]>>[OH:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[CH:13]=[CH:12][C:11]([CH:14]=[N:18][OH:19])=[CH:10][C:9]=2[CH3:16])=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 443297Hydroxyamine hydrochlorideHCID 85977671HCID 85977671, compound

Product 1

HCID 136338601HCID 136338601, compound

Procedure

The title compound was prepared by reacting 4′-hydroxy-2-methyl-1,1′-biphenyl-4-carbaldehyde (350 mg, 1.65 mmol) with hydroxylamine hydrochloride (230 mg, 3.30 mmol) according to Method C to yield 360 mg (96%) of white solid: mp 169-171° C.;

Sources & evidence

ORD record
ord-15da572590864a3592588a5da89ec172
Source dataset
uspto-grants-2007_10
Patent number
US07279600B2

Reaction notes

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