huagongshe.com
HRID1180632

反应详情

EQUATION

反应方程式

HRID 1180632 的结构方程式

REACTANTS

反应物

3
结构：OB(O)c1ccc(Cl)cc1
HCID74299

Benzeneboronic acid, p-chloro-

C6H6BClO2

结构：CC1(C)OB(c2ccc3c(c2)C[C@H]2CC[C@@H](C3)[C@]23CN(CC(F)(F)F)S(=O)(=O)N3)OC1(C)C
HCID23571079

未命名化合物

结构：Brc1c[nH]cn1
HCID178418934

未命名化合物

PRODUCTS

生成物

1
结构：O=S1(=O)N[C@@]2(CN1CC(F)(F)F)[C@@H]1CC[C@H]2Cc2ccc(-c3cn(-c4ccc(Cl)cc4)cn3)cc2C1
HCID23571067

未命名化合物

PROCEDURE

实验过程

Prepared from 4-bromo-1H-imidazole, 4-chlorophenylboronic acid and homochiral boronate from Example 24 Step 1 following the procedures in Example 76 Steps 1 and 2. δ (1H, 500 MHz, CDCl3) 1.34-1.42 (2H, m), 1.68-1.75 (2H, m), 2.42-2.50 (2H, m), 2.70-2.82 (2H, m), 3.20-3.28 (2H, m), 3.44 (2H, s), 3.68 (2H, q, J=8.7 Hz), 4.68 (1H, s), 7.12 (1H, d, J=7.8 Hz), 7.38 (2H, d, J=8.7 Hz), 7.47-7.51 (3H, m), 7.56 (1H, d, J=7.8 Hz), 7.62 (1H, s), 7.86 (1H, s). MS (ES+) 537, 539 ([MH]+).