4-Chlorophenylboronic acid → CID 23571067

Participants

Role	Name	HCID	Charge
Reactant	4-Chlorophenylboronic acid	HCID 74299	—
Reactant	[6s,9r,11r]2',3',4',5,5',6,7,8,9,10-Decahydro-2-(4,4,5,5-tetramethyl-[1,3,2]-dioxaborolan-2-yl)-5'-(2,2,2-trifluoroethyl)spiro[6,9-methanobenzocyclooctene-11,3'-[1,2,5]thiadiazole]1',1'-dioxide	HCID 23571079	—
Reactant	HCID 178418934	HCID 178418934	—
Product	CID 23571067	HCID 23571067	—

Reaction Steps

Prepared from 4-bromo-1H-imidazole, 4-chlorophenylboronic acid and homochiral boronate from Example 24 Step 1 following the procedures in Example 76 Steps 1 and 2. δ (1H, 500 MHz, CDCl3) 1.34-1.42 (2H, m), 1.68-1.75 (2H, m), 2.42-2.50 (2H, m), 2.70-2.82 (2H, m), 3.20-3.28 (2H, m), 3.44 (2H, s), 3.68 (2H, q, J=8.7 Hz), 4.68 (1H, s), 7.12 (1H, d, J=7.8 Hz), 7.38 (2H, d, J=8.7 Hz), 7.47-7.51 (3H, m), 7.56 (1H, d, J=7.8 Hz), 7.62 (1H, s), 7.86 (1H, s). MS (ES+) 537, 539 ([MH]+).

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07282513B2
Source dataset	uspto-grants-2007_10
ORD ID	ord-d14715779c96481394619596d83aa06b
Source note	uspto-grants-2007_10