反应详情

Prepared from 4-bromo-1H-imidazole, 3,4-difluorophenylboronic acid and homochiral boronate from Example 24 Step 1 following the procedures in Example 76 Steps 1 and 2. □ (1H, 400 MHz, CDCl3) 1.18-1.24 (2H, m), 1.70-1.73 (2H, m), 2.43-2.49 (2H, m), 2.69-2.81 (2H, m), 3.20-3.26 (2H, m), 3.44 (2H, s), 3.68 (2H, q, J=8.7 Hz), 4.72 (1H, s), 7.13 (1H, d, J=7.8 Hz), 7.19-7.22 (1H, m) 7.28-7.35 (2H, m), 7.48 (1H, d, J=1 Hz), 7.54 (1H, dd, J=7.7, 2 Hz), 7.61 (1H, s), 7.83 (1H, d, J=1 Hz). MS (ES+) 539 ([MH]+).