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HRID1180637

反应详情

EQUATION

反应方程式

HRID 1180637 的结构方程式

REACTANTS

反应物

3
结构：OB(O)c1ccccc1F
HCID2734354

(2-Fluorophenyl)boronato(2-)

C6H6BFO2

结构：CC1(C)OB(c2ccc3c(c2)C[C@H]2CC[C@@H](C3)[C@]23CN(CC(F)(F)F)S(=O)(=O)N3)OC1(C)C
HCID23571079

未命名化合物

结构：Brc1c[nH]cn1
HCID178418934

未命名化合物

PRODUCTS

生成物

1
结构：O=S1(=O)N[C@@]2(CN1CC(F)(F)F)[C@@H]1CC[C@H]2Cc2ccc(-c3cn(-c4ccccc4F)cn3)cc2C1
HCID23571063

未命名化合物

PROCEDURE

实验过程

Prepared from 4-bromo-1H-imidazole, 2-fluorophenylboronic acid and homochiral boronate from Example 24 Step 1 following the procedures in Example 76 Steps 1 and 2. δ (1H, 360 MHz, CDCl3) 1.92-1.97 (2H, m), 2.26-2.29 (2H, m), 3.01-3.03 (2H, m), 3.29-3.36 (2H, m), 3.76-3.82 (2H, m), 4.00 (2H, s), 4.24 (2H, q, J=8.8 Hz), 5.28 (1H, s), 7.69 (1H, d, J=7.8 Hz), 7.84-7.88 (2H, m), 7.90-7.98 (1H, m), 7.99-8.05 (1H, m), 8.08-8.13 (2H, m), 8.19 (1H, s), 8.42 (1H, s). MS (ES+) 521 ([MH]+).