HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Fluorophenylboronic acid → CID 23571063
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Fluorophenylboronic acid | HCID 2734354 | — |
| Reactant | [6s,9r,11r]2',3',4',5,5',6,7,8,9,10-Decahydro-2-(4,4,5,5-tetramethyl-[1,3,2]-dioxaborolan-2-yl)-5'-(2,2,2-trifluoroethyl)spiro[6,9-methanobenzocyclooctene-11,3'-[1,2,5]thiadiazole]1',1'-dioxide | HCID 23571079 | — |
| Reactant | HCID 178418934 | HCID 178418934 | — |
| Product | CID 23571063 | HCID 23571063 | — |
Reaction Steps
Prepared from 4-bromo-1H-imidazole, 2-fluorophenylboronic acid and homochiral boronate from Example 24 Step 1 following the procedures in Example 76 Steps 1 and 2. δ (1H, 360 MHz, CDCl3) 1.92-1.97 (2H, m), 2.26-2.29 (2H, m), 3.01-3.03 (2H, m), 3.29-3.36 (2H, m), 3.76-3.82 (2H, m), 4.00 (2H, s), 4.24 (2H, q, J=8.8 Hz), 5.28 (1H, s), 7.69 (1H, d, J=7.8 Hz), 7.84-7.88 (2H, m), 7.90-7.98 (1H, m), 7.99-8.05 (1H, m), 8.08-8.13 (2H, m), 8.19 (1H, s), 8.42 (1H, s). MS (ES+) 521 ([MH]+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07282513B2 |
| Source dataset | uspto-grants-2007_10 |
| ORD ID | ord-f6ba69f519724ec68be375c1992cdd10 |
| Source note | uspto-grants-2007_10 |