Acetone → HCID 11565921, compound

HRID 1180676Notes

Reaction equation

HRID 1180676 reaction equation
[CH2:1]([S:11]([OH:14])(=[O:13])=[O:12])[CH2:2][S:3][S:4][CH2:5][CH2:6][S:7]([OH:10])(=[O:9])=[O:8].[OH-].[NH4+:16].CC(C)=O>O>[CH2:1]([S:11]([O-:14])(=[O:13])=[O:12])[CH2:2][S:3][S:4][CH2:5][CH2:6][S:7]([O-:10])(=[O:8])=[O:9].[NH4+:16].[NH4+:16]

Participants

5

Reactant 3

HCID 180AcetoneHCID 14923Ammonium Hydroxide2×HCID 656262,2'-Dithiodiethanesulfonic acid

Product 1

HCID 11565921HCID 11565921, compoundYield 82%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

A solution of 2,2′-dithiobis ethane sulfonic acid (2.5 g, containing 9% water, 8.1 mmol) in water (1.0 mL) was titrated with ammonium hydroxide aqueous solution (28-30% concentration, Aldrich) until the pH of the reaction solution was adjusted to 7.0. Overall 2.6 mL of ammonium hydroxide was used. Acetone (200 mL) was added to the reaction solution to precipitate the product. The resulting white solid was isolated by filtration and dried under high vacuum to give 2.10 g of product (82% yield). The purity of the product was 98.2% from HPLC analysis.

Workup

  1. customto precipitate the product
  2. customThe resulting white solid was isolated by filtration
  3. customdried under high vacuum

Sources & evidence

ORD record
ord-bb494aa9233f46c7aad67a7936d7efeb
Source dataset
uspto-grants-2007_10
Patent number
US07282602B2

Reaction notes

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