Cyclobutane-1,1-diyldimethanol → HCID 11266095, compound

HRID 1180784Notes

Reaction equation

HRID 1180784 reaction equation
[OH:1][CH2:2][C:3]1([CH2:7][OH:8])[CH2:6][CH2:5][CH2:4]1.Cl[C:10]1[N:11]=[N:12][C:13]([CH3:22])=[CH:14][C:15]=1[C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1>>[CH3:22][C:13]1[N:12]=[N:11][C:10]([O:1][CH2:2][C:3]2([CH2:7][OH:8])[CH2:6][CH2:5][CH2:4]2)=[C:15]([C:16]2[CH:17]=[CH:18][CH:19]=[CH:20][CH:21]=2)[CH:14]=1

Participants

3

Reactant 2

HCID 4498243Cyclobutane-1,1-diyldimethanolHCID 64152403-chloro-6-methyl-4-phenylpyridazine

Product 1

HCID 11266095HCID 11266095, compound

Procedure

The title compound was prepared using the same experimental procedure as in example 25a from [1-(hydroxymethyl)cyclobutyl]methanol and 3-chloro-6-methyl-4-phenylpyridazine. 1H NMR (300 MHz, CDCl3) δ 7.58-7.25 (m, 6H), 4.64 (s, 2H), 3.59 (d, J=6 Hz, 2H), 3.05 (t, J=7 Hz, 1H), 2.63 (s, 3H), 2.00-1.73 (m, 6H). GC-MS m/z 285 (M+H).

Sources & evidence

ORD record
ord-cdda63c94333461487c49f7fc3011db4
Source dataset
uspto-grants-2007_10
Patent number
US07282512B2

Reaction notes

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