HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-{1-[(Benzyloxy)methyl]cyclobutyl}ethanethioamide → {1-[(4-Methyl-1,3-thiazol-2-yl)methyl]cyclobutyl}methanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-{1-[(Benzyloxy)methyl]cyclobutyl}ethanethioamide | HCID 11265176 | — |
| Reactant | 1-Bromo-4,4,4-trifluoro-2-butanone | HCID 21100202 | — |
| Product | {1-[(4-Methyl-1,3-thiazol-2-yl)methyl]cyclobutyl}methanol | HCID 58979694 | — |
Reaction Steps
The title compound was prepared using the same experimental procedure as in examples 18f and 18g from 2-{1-[(benzyloxy)methyl]cyclobutyl}ethanethioamide and 1-bromo-4,4,4-trifluoro-2-butanone. 1H NMR (300 MHz, CDCl3) δ 7.25 (s, 1H), 3.35 (s, 2H), 2.82 (br s, 2H), 2.02-1.91 (m, 6H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07282512B2 |
| Source dataset | uspto-grants-2007_10 |
| ORD ID | ord-fadf44fe503d4920ac461fde20fa6ea6 |
| Source note | uspto-grants-2007_10 |