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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1181061Generated: November 4, 2026

Toluene-4-sulfonic acid 2-[2-(4-bromophenyl)-5-methyloxazol-4-yl]ethyl ester → HCID 69232919, compound

https://huagongshe.com/reaction/1181061

Reaction equation

Participants

RoleNameHCIDCharge
ReactantToluene-4-sulfonic acid 2-[2-(4-bromophenyl)-5-methyloxazol-4-yl]ethyl esterHCID 58979135—
Reactant3-[4-Hydroxy-2-(isopropoxycarbonylamino-methyl)-phenyl]-propionic acid tert-butyl esterHCID 58979470—
ProductHCID 69232919HCID 69232919127.1%

Reaction Steps

Toluene-4-sulfonic acid 2-[2-(4-bromo-phenyl)-5-methyl-oxazol-4-yl]-ethyl ester (5.06 g, 11.6 mmol) and 3-[4-hydroxy-2-(isopropoxycarbonylamino-methyl)-phenyl]-propionic acid tert-butyl ester (3.01 g, 8.92 mmol) were coupled using Standard procedure A to give the title compound as a white solid (3.41 g, 64%). MS [ES] m/z 601.603 (M+H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07282501B2
Source datasetuspto-grants-2007_10
ORD IDord-1adc0363e3484812ade7299ec5239026
Source noteuspto-grants-2007_10