HRID1181071

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CC(C)OC(=O)NCc1cc(O)ccc1CCC(=O)OC(C)(C)C

HCID58979470

未命名化合物

结构：Cc1ccc(S(=O)(=O)OCCc2nc(-c3ccc([N+](=O)[O-])cc3)oc2C)cc1[N+](=O)[O-]

HCID58979495

未命名化合物

PRODUCTS

生成物

结构：Cc1oc(-c2ccc([N+](=O)[O-])cc2)nc1CCOc1ccc(CCC(=O)OC(C)(C)C)c(CNC(=O)OC(C)C)c1

HCID58979358

未命名化合物

PROCEDURE

实验过程

4-Methyl-3-nitro-benzenesulfonic acid 2-[5-methyl-2-(4-nitro-phenyl)-oxazol-4-yl]-ethyl ester (Preparation 7) and 3-[4-hydroxy-2-(isopropoxycarbonylamino-methyl)-phenyl]-propionic acid tert-butyl ester were coupled by Standard procedure A to give the title compound.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-c547cf59481e489e993c50805e0d2c91
来源数据集: uspto-grants-2007_10
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07282501B2
来源说明: uspto-grants-2007_10

反应 SMILES

[CH3:1][C:2]1[O:6][C:5]([C:7]2[CH:12]=[CH:11][C:10]([N+:13]([O-:15])=[O:14])=[CH:9][CH:8]=2)=[N:4][C:3]=1[CH2:16][CH2:17][O:18]S(C1C=CC(C)=C([N+]([O-])=O)C=1)(=O)=O.[C:32]([O:36][C:37](=[O:55])[CH2:38][CH2:39][C:40]1[CH:45]=[CH:44][C:43](O)=[CH:42][C:41]=1[CH2:47][NH:48][C:49]([O:51][CH:52]([CH3:54])[CH3:53])=[O:50])([CH3:35])([CH3:34])[CH3:33]>>[C:32]([O:36][C:37](=[O:55])[CH2:38][CH2:39][C:40]1[CH:45]=[CH:44][C:43]([O:18][CH2:17][CH2:16][C:3]2[N:4]=[C:5]([C:7]3[CH:8]=[CH:9][C:10]([N+:13]([O-:15])=[O:14])=[CH:11][CH:12]=3)[O:6][C:2]=2[CH3:1])=[CH:42][C:41]=1[CH2:47][NH:48][C:49]([O:51][CH:52]([CH3:53])[CH3:54])=[O:50])([CH3:35])([CH3:34])[CH3:33]